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Zebrafish (Danio Rerio) have emerged as one of the leading model for studying the development and modeling of human disease.

These little teleost fish present many advantages:

  • very rapid embryonic development (all major organs are formed within 3 days)
  • transparency of the embryos (allowing visual observations of internal structures and non-invasive imaging)
  • short generation time (zebrafish are sexually mature after 3-4 months)
  • high fecundity (a single female can lay up to 150  eggs per clutch et per week allowing powerful statistics)
  • high genetic homology to humans (about 75% of the human genome has functional homologs with zebrafish)
updated on 9/27/18

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